Journal Watch
PD and Bone Mineral Disorders vs. HD
Body composition, nutritional status, DEXA, and bone mineral disease (BMD) biomarkers were assessed at baseline and one year in 242 ESRD patients starting either PD (n=138) or HD (n=104). Among HD patients, BMD decreased significantly—but not in PD patients. Preservation of BMD was associated with significantly lower all-cause mortality, with cortical bone preservation more predictive than trabecular bone preservation.
Read the abstract » | (added 2020-09-11)
Tags: End stage Renal Disease, Bone Mineral Density, Dialysis
SARS-CoV-2 in PD Effluent
Analysis of bodily fluids from 3 SARS-CoV-2-infected PD patients found that, while viral load was quite high in nasopharyngeal swabs, none of the PD effluent tested positive, even after dialysate concentration. This suggests that the risk of virus transmission from used PD fluid may be low.
Read the abstract » | (added 2020-09-11)
Tags: COVID 19, SARS CoV 2, Peritoneal Dialysis
PD vs. Standard HD for Cognitive Function
A metaanalysis of papers including 195,774 patients looked at whether PD or standard in-center HD better supported cognitive function. The authors found significantly less risk of cognitive impairment among those who did PD.
Read the abstract » | (added 2020-09-11)
Tags: Cognitive, Renal Failure
Benefits of PD Remote Monitoring
A retrospective study compared two groups of APD patients, one that received remote monitoring (n=38) and one that received routine care (n=35). PD dropout and fluid status were similar between the two groups. But, the remote monitoring group had fewer ER and hospital visits related to kidney disease, especially among those with more comorbidities. Patients also preferred remote monitoring, and were more satisified with their care.
Read the abstract » | (added 2020-09-11)
Tags: Clinical Outcomes, Quality Of Life, Remote Monitoring, Telemedicine
Impact of Depression on PD Patient and Technique Survival
Among 275 patients who had done CAPD for at least 3 months, 31.3% tested as having depressive symptoms. Long-term patient and technique survival were significantly poorer in this group, even adjusting for cofounders.
Read the abstract » | (added 2020-09-11)
Quanta SC+ Fluid Removal Accuracy
Through both passive and active fluid control mechanisms, the Quanta SC+ home HD machine was accurate to within 1 mL per hour for flow balance and to within 13 mL/hr for ultrafiltration.
Read the abstract » | (added 2020-08-11)
Serum Uric Acid and Residual Kidney Function in PD
In a study of 201 CAPD patients followed for up to 8 years (median 23.43+ 16.6 months), high or low serum uric acid and peritonitis were independent risk factors for loss of all residual kidney function. Higher weekly Kt/V urea helped protect residual function.
Read the abstract » | (added 2020-08-11)
Tags: Residual Renal Function, Uric Acid
Carnitine Deficiency and ESA Resistance in PD
Among 60 PD patients, 56 had carnitine deficiency, which was found to independently predict ESA resistance.
Read the abstract » | (added 2020-08-11)
Tags: Carnitine Deficiency, Peritoneal Dialysis, Erythropoietin Resistance Index
C-reactive Protein to Albumin Ratio (CAR) on PD Predicts Survival
An analysis of 758 PD patients observed for up to 12 years found that those whose CAR was lower were significantly more likely to survive than those whose CAR was higher.
Read the abstract » | (added 2020-08-11)
Tags: Serum C reactive Protein To Albumin Ratio, Serum C reactive Protein, PD, Peritoneal Dialysis
How Much Dialysate Should be Used for Nocturnal HD With NxStage?
Predictive modeling finds that the dialysate lactate concentration used for short daily HD may not be appropriate for nocturnal HD. Since the effect of lactate mainly depends on weekly dialysate volume, reducing from 60 to 30 liters for frequent nocturnal HD may be appropriate.
Read the abstract » | (added 2020-08-11)
Tags: Home Hemodialysis, Lactate, Acid Generation, Dialysate