Journal Watch
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Preventing PD Infections: ASN Core Interventions
An ASN workshop developed interventions focused on six key, evidence-based strategies to reduce infection, improve quality of life, and expand home treatments: Infection rate surveillance and feedback, standardized staff training/competency assessment, standardized patient and care partner education, routine infection prevention assessments, antimicrobial PD exit site prophylaxis, and prophylactic antimicrobials for some procedures or events.
Read the abstract » | (added 2025-12-17)
Tags: Interventions, Infection, Quality Of Life, Home Treatments, Training
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Optimal Education for Optimal Start Dialysis
Optimal ESRD start patients receive a preemptive kidney transplant, start a home therapy, or begin in-center HD with a venous access, and optimal education is needed for these events to occur. This paper explores gaps in modality education in outpatient nephrology clinics, dialysis clinics, and inpatient settings.
Read the abstract » | (added 2025-12-17)
Tags: Optimal Start Dialysis, Optimal Education, Modality Education
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Blood Pressure Variability: Is PD or Standard HD Better?
In a prospective cohort of 156 PD patients and 218 HD patients (n=374), clinical and lab data and 24-hour ambulatory BP were measured. After 4 years of follow-up, PD patients had significantly lower 24-hour systolic BP and a significantly lower (p = 0.039) incidence of cardiovascular events. BVP was higher in HD patients.
Read the abstract » | (added 2025-12-17)
Tags: Blood Pressure Variability, Cerebrovascular Risk, Hemodialysis, Peritoneal Dialysis
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Women May Fare Better on PD Than Men
The International observational PDOPPS has turned its attention to the examination of sex differences in PD outcomes like mortality, transfer to HD, peritonitis, and transplant rates. PD patients from eight countries (n=25,292) were 43% female on average, and females had lower mortality rates, fewer transfers to HD, and lower rates of peritonitis. In South Korea, for example, median time on PD was 6.4 years for females, but just 4.9 years for males.
Read the abstract » | (added 2025-12-17)
Tags: PDOPPS, Gender, PD Outcomes, Mortality, Transfer To HD, Peritonitis, Transplant Rates
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Body Mass Index and PD: A Meta-analysis
Analysis of adjusted data from 18 studies found that underweight PD patients had a significantly higher risk of mortality than those with normal BMI, though obesity did not. However, obese PD patients had a significant increase in the risk of peritonitis. Neither underweight nor obesity increased the risk of technique failure or transfer to HD.
Read the abstract » | (added 2025-11-11)
Tags: Body Mass Index, PD, Meta analysis
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Pregnancy in Women on Home Dialysis
Home therapies offer advantages for women who are able to become pregnant, including flexibility, improved hemodynamic stability, and better fetal outcomes. Pregnancy management requires close obstetric monitoring, multidisciplimnary care, and optimized nutrition and anemia management.
Read the abstract » | (added 2025-11-11)
Tags: Home Dialysis, Pregnancy, Outcomes
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A U.S. Staff-assisted PD Program
In a Satellite Dialysis trial, patient care technicians were trained to offer PD and troubleshoot common issues. From an initial two clinics, the program expanded to 16 by October, 2022. Of 121 patients referred to the program, 73 received staff assisted for a total of 604 visits lasting 1-84 days. Patients most often needed help with PD set up and correctly following the steps. Most needed only short-term transitional assistance, and 93% were discharged from the program without staff assistance.
Read the abstract » | (added 2025-11-11)
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PDOPPS on Incremental PD Starts and Clinical Outcomes
What dose should be offered at the start of incremental PD? An international prospective cohort study assessed 1,365 patients from 128 clinics in seven countries who began standard (63%) or incremental (37%) PD within3 months of January 1, 2014 until December 31, 2017. There was no significant difference in transfer to HD between the standard PD (15%/year) and incremental PD (14%/year), nor were there differences between groups in peritonitis or mortality.
Read the abstract » | (added 2025-11-11)
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PD Predict: A Machine Learning Model for PD Survival
A retrospective cohort study of 14,650 patients in the UK Renal Registry was split into two test sets: development and internal testing. The model produced a Harrell’s concordance index of 0.80 during temporal validation, while external validation done in Norway was 0.77. This result outperforms traditional predictive methods.
Read the abstract » | (added 2025-11-11)
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First-in-human Trial of Sorbent-assisted Continuous Flow PD
One downside of peritoneal dialysis (PD) is the need to truck bags of sterile fluid to patients. A new sorbent-assisted PD (SAPD) device regenerates spent dialysate. SAPD may improve uremic solute clearance by maintaining a high concentration gradient and increasing the mass transfer area coefficient. It may help preserve peritoneal membranes longer by avoiding high glucose concentrations. And, fewer connections may mean less peritonitis. Short-term safety and performance of SAPD will be evaluated in a group of 12 stable adulte PD patients.
Read the abstract » | (added 2025-10-14)
Tags: First in human Trial, Continuous Flow Peritoneal Dialysis, Sorbent assisted Peritoneal Dialysis, Sapd, Peritonitis