Journal Watch
Exercise in PD Patients and Residual Renal Function
After a 12-week home-based exercise program was completed, researchers analyzed residual renal function among 13 patients who received usual care and 16 who had been in the exercise intervention group. Urinary liver-type fatty acid-binding protein and microalbumin-to-creatinine ratios were significantly lower in the exercise group, suggesting a possible benefit.
Read the abstract » | (added 2020-02-19)
Tags: Exercise, Renal Outcome, Residual Renal Function, Peritoneal Dialysis
Home HD: Hospitalizations and Technique Survival
In a Swedish registry study, patients initiating PD (n=456), home HD (n=152), and in-center HD (IHD; n=608) were matched by age, sex, comorbidity, and start date. Patients using home HD had significantly lower hospital admissions and days than those doing PD or IHD (1.7, 12 days vs. 2.8, 20 days and 2.2, 14 days respectively). Home HD patients also had significantly fewer admissions for cardiovascular diagnoses or infectious disease, as well as significantly longer technique survival.
Read the abstract » | (added 2020-01-09)
Tags: PD, Home HD, In center HD, Hospital Admissions, Cardiovascular Diagnosis, Infectious Disease, Technique Survival
First European Patients Using Nocturnal Home HD with Low-flow Dialysate
A retrospective analysis looked at 21 patients using low-flow dialysate for nocturnal home HD and followed for a minimum of 12 months. Participants had a mean dialysis duration of 28 hours per week; most used alternate nights and 50-60 L of dialysate per session. Use of phosphate binders and blood pressure medications was significantly reduced, and no patient safety events were reported.
Read the abstract » | (added 2020-01-09)
Tags: Low flow Dialysate, Nocturnal Home HD, Phosphate Binders, Blood Pressure Medication
PD vs. In-center HD for Sudden Cardiac Death
A Korean registry study of 132,083 PD and in-center HD patients followed between 1985 and 2017 analyzed 34,532 deaths. Sudden cardiac death (SCD) was responsible for 19.6% of deaths on PD and 22.2% of deaths on in-center HD. Even after adjusting for age and comorbidities, the risk of SCD was higher with HD.
Read the abstract » | (added 2020-01-09)
Tags: PD, In center HD, Sudden Cardiac Death
Low-dose IV Iron Sucrose for Treatment of Anemia in PD
A small study (n=18) of IV iron sucrose (200mg loading dose followed by 100mg monthly for 5 consecutive months) found reductions in ESA dosing for 5 patients and discontinuation in one, with no reported side effects.
Read the abstract » | (added 2020-01-09)
Tags: IV Iron Sucrose, Anemia, ESA Dosing
A Novel Surgical Technique for Urgent Start PD
Placing a PD catheter with a double purse-string around the inner cuff was safe and feasible for urgent start PD, finds a study of 135 catheter insertions between 2011 and 2018. Double-cuffed straight Tenckhoff catheters were implanted surgically or semi-surgically using the double purse-string technique, and the incidence of leakages, dislocations, peritonitis, and exit-site infection were low. There were no bleeding events, bowel perforations, or hernia formations.
Read the abstract » | (added 2020-01-09)
Impact of a Nurse-led Protocol on PD Fluid Overload
Among PD patients divided into a group symptomatic of fluid overload (>2L; n=53) and a group that was not (n=50), a 12-week nurse-led education and motivation intervention—with hypertonic cycles for short-term relief of fluid overload—significantly reduced overhydration. Knowledge and adherence were both significantly improved as well.
Read the abstract » | (added 2020-01-09)
Diabetes and the Risk of Peritonitis on PD
In contrast to earlier reports, a single-center study of PD patients between 1980 and 2012 (by era: 1980-’93, 1994-’04, 2005-12) found that while PD-associated peritonitis was higher among patients with diabetes in the earlier two eras, there were no differences in recent years.
Read the abstract » | (added 2020-01-09)
Tags: PD, Peritonitis, Diabetes
Factors Associated with Fatigue in PD Patients
Analysis of fatigue scale data from 108 PD patients in China revealed that 78.7% suffered from fatigue, a number significantly higher than in the community population. Associated factors included sleep quality, normalized protein nitrogen appearance, transferrin, alkaline phosphatase, and total cholesterol levels.
Read the abstract » | (added 2020-01-09)
Tags: Fatigue, PD, Sleep Quality, Protein Nitrogen Appearance, Transferrin, Alkaline Phosphatase, Total Cholesterol Levels
European Patients Live Longer with Extended HD Treatments
Compared to standard in-center HD, patients from eight European countries who dialyzed for 6+ hours thrice weekly lived longer. Of 142,460 patients, 1,338 did extended HD. Compared to in-center HD (13.5/100 person-years), crude mortality for extended HD (6.0/100 person-years) was significantly better. Overall, those treated with extended treatments were 73% more likely to have survived.
Read the abstract » | (added 2019-12-10)
Tags: Survival, Extended hours Hemodialysis, Haemodialysis, ERA EDTA Registry