Journal Watch
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Carnitine Deficiency and ESA Resistance in PD
Among 60 PD patients, 56 had carnitine deficiency, which was found to independently predict ESA resistance.
Read the abstract » | (added 2020-08-11)
Tags: Carnitine Deficiency, Peritoneal Dialysis, Erythropoietin Resistance Index
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Home HD Respite Care Resource Implications
A Canadian analysis of 119 home HD patients found that 66% required 292 back-up, in-center HD sessions during 96 patient years; 53% for vascular access issues.
Read the abstract » | (added 2020-08-11)
Tags: Home Hemodialysis, Resource Utilization, Technique Survival
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How Much Dialysate Should be Used for Nocturnal HD With NxStage?
Predictive modeling finds that the dialysate lactate concentration used for short daily HD may not be appropriate for nocturnal HD. Since the effect of lactate mainly depends on weekly dialysate volume, reducing from 60 to 30 liters for frequent nocturnal HD may be appropriate.
Read the abstract » | (added 2020-08-11)
Tags: Home Hemodialysis, Lactate, Acid Generation, Dialysate
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Outcomes in Urgent- vs. Early-Start PD
A study defining urgent-start PD (US-PD) as within 72 hours of catheter placement and early start (ES-PD) as 3 and 14 days later compared 72 patients in both groups. Both groups were comparable re: demographics, 30-day complications, 6-month hospitalizations, and PD dropout. US-PD patients were more prone to leakage.
Read the abstract » | (added 2020-07-10)
Tags: Peritoneal Dialysis, Disease Patients, Clinical Characteristics
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PD Probiotics, Malnutrition, and Health-related Quality of Life
In a controlled trial that randomized 116 PD patients into a probiotic and a control group, 2 months of probiotics reduced inflammation markers (HS-CRP and IL-6), and significantly improved serum albumin, upper arm circumference, and triceps skinfold thickness. The probiotic group also had higher physical and social functioning scores.
Read the abstract » | (added 2020-07-10)
Tags: Biochemical, Physical Functioning, Probiotic Supplementation
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Dialysis Adequacy Predicts Sexual Function
A study comparing men and women doing HD (n=70) or PD (n=57) to healthy male (n=65) and female (n=48) volunteers assessed sexual function, depression, anxiety, and health-related quality of life. In men, dialysis adequacy was the most important factor in sexual function. In women, dialysis adequacy and depression were both significant. Inadequate dialysis worsened sexual function and was associated with more anxiety and depression, and—in men—reduced health-related quality of life.
Read the abstract » | (added 2020-07-10)
Tags: Adecuación De Diálisis, Ansiedad, Anxiety, Dialysis Adequacy
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Starting with PD Better than Switching to it from HD
A metaanalysis comparing patients who started with PD to those who began HD and then switched to PD after 3 months found significantly better overall and technique survival in the PD first group. There were no significant differences in the peritonitis rate.
Read the abstract » | (added 2020-07-10)
Tags: Hemodialysis, Peritoneal Dialysis, Renal Replacement Therapy
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Soy Isoflavones Reduce Heart Disease Risk Factors in PD
A trial randomly assigned 40 PD patients to a soy isoflavone or placebo group, and took several measures of inflammation at baseline and 8 weeks. At the end of the study, those in the soy group had significant decreases in serum VCAM-1 and serum ICAM-1, two cardiovascular disease risk factors in PD patients
Read the abstract » | (added 2020-06-10)
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Does Extended Hour HD Helps Survival After Returning to Standard HD?
In an analysis of data from the ACTIVE Dialysis Trial, 200 standard HD patients were randomly assigned to 12 or 24 hours of treatment per week for a year, with follow up at 24, 36, and 60 months after a return to 12 hours of treatment per week. Long-term survival was not improved.
Read the abstract » | (added 2020-06-10)
Tags: Mortality, End Stage Kidney Disease, Hemodialysis, Randomized Controlled Trial
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10-year PD Survival
In a group of 533 incident PD patients (mean starting age of 48 +16 years) followed from 2006 until 2018, survival at 1 year was 93%, at 3 years 81%, at 5 years 64%, and at 10 years 36%. Encapsulating peritoneal sclerosis (EPS) occurred in 1.3%.
Read the abstract » | (added 2020-06-10)