Journal Watch
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First-in-human Trial of Sorbent-assisted Continuous Flow PD
One downside of peritoneal dialysis (PD) is the need to truck bags of sterile fluid to patients. A new sorbent-assisted PD (SAPD) device regenerates spent dialysate. SAPD may improve uremic solute clearance by maintaining a high concentration gradient and increasing the mass transfer area coefficient. It may help preserve peritoneal membranes longer by avoiding high glucose concentrations. And, fewer connections may mean less peritonitis. Short-term safety and performance of SAPD will be evaluated in a group of 12 stable adulte PD patients.
Read the abstract » | (added 2025-10-14)
Tags: First in human Trial, Continuous Flow Peritoneal Dialysis, Sorbent assisted Peritoneal Dialysis, Sapd, Peritonitis
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Using a B. Braun Machine for Home HD
Successful use of a B. Braun machine for home HD required more space in the home, a dedicated reverse osmosis system, specialized plumbing and electrical connections, and machine-specific patient training. Most patients found these home requirements manageable and the machine easy to use for daytime or nocturnal treatments.
Read the abstract » | (added 2025-10-14)
Tags: B. Braun Machine, Home HD, Machine Requirements, Machine specific Patient Training
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Meta-analysis of Factors in PD Catheter-related Infections
Thirteen studies were included in a meta-analysis that found PD catheter-infection factors included diabetes, insecure catheter fixation, >2 years on dialysis, BMI >20 kg/m2, mechanical strain, lack of proper care, irregular caregivers, and a history of catheter pulling.
Read the abstract » | (added 2025-10-14)
Tags: PD, Catheter related Infections, Risk Factors, Meta analysis
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ASN: Improving Fellows Education for Home Dialysis
Inadequate fellows training has been identified as one reason home therapies are underutilized in the U.S. In response, the American Society of Nephrology developed a virtual home dialysis university (ASN-HDU) in 2023. A mixed-methods evaluation sampled participants who attended both the live and virtual HDU programs or only the live one. A post-HDU survey and 8-month follow up survey assessed quantitative changes in attendees comfort with home dialysis. Ten interviews were also conducted to identify themes. ASN-HDU participants reported higher comfort levels for PD and home HD, while the program filled many—but not all—identified gaps.
Read the abstract » | (added 2025-10-14)
Tags: ASN HDU, Fellows Training, Home Dialysis
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ISPD Position Paper: Teaching PD
The International Society for Peritoneal Dialysis adds a new 2025 Position Paper that builds on two prior works to help clinicians teach patients/care partners. Key areas include education, knowledge, skills, and attributes for PD nurse trainers; preparation for training; methods/interventions; post-training; and outcomes measures.
Read the abstract » | (added 2025-10-14)
Tags: ISPD, Teaching PD, Care Partners, Post Training, Outcome Measures
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Amino acid and protein losses in adult patients receiving maintenance dialysis: a literature review
Patients on dialysis lose amino acids/protein on HD, hemodiafiltration (HDF). home HD, peritoneal dialysis (PD) and nocturnal HD (NHD). Protein losses were greater with HDF compared to HD. Patients on daily PD lose more amino acids/protein than those on HD.
Read the abstract » | (added 2025-09-15)
Tags: Amino Acids, Protein Loss, Dialysis
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Challenges and Opportunities in Managing Individuals with Obesity on Peritoneal Dialysis
Some view obesity as a contraindication to PD, which limits treatment options for many patients. However, PD can be successfully utilized by people with obesity! Careful planning of the exit site can help.
Read the abstract » | (added 2025-09-15)
Tags: Obesity, Peritoneal Dialysis, Exit Site
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Chlorhexidine vs. Ethanol for Buttonhole AVF Disinfection
A randomized, cross-over trial compared 5mg/mL chlorhexidine in 70% ethanol vs. 70% ethanol alone in four dialysis treatments. Factors considered were arm washing, serial sampling of normal skin flora immediately before/after disinfection, and 2 and 4 hours after disinfection. Buttonhole scabs were collected and compared to each patient’s normal skin flora. Chlorhexidine was more effective than ethanol alone.
Read the abstract » | (added 2025-08-21)
Tags: Chlorhexidine, Ethanol, Skin Flora, Disinfection, AV Fistula, Buttonhole
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Diabetes + PD + Self-management: Theory of Planned Behavior (TPB)
Semi-structured interviews formulated with TPB were conducted with 16 diabetic kidney disease (DKD) PD patients. Analysis identified 3 themes and 7 sub-themes related to physical and mental perception, emotions, subjective norm, continuity of care, social feedback, perceived behavioral control, and limitations on external resources. Strengthening positive feedback and social support can improve active patient participation in decision-making.
Read the abstract » | (added 2025-08-21)
Tags: Diabetic Kidney Disease, Diabetes, PD, Self management, Theory Of Planned Behavior
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Black and Latino Patients: Staying on PD
Black and Latino patients are disproportionately affected by ESKD, less likely to use PD, and more likely to switch to in-center HD if they do start PD. In-depth, semistructured interviews with twelve Black and eight Latino patients who were currently or previously receiving PD found that poor mental health, medicalization of the home, and language and cultural barriers were factors in PD dropout.
Read the abstract » | (added 2025-08-21)
Tags: Ethnicity, ESKD, PD, PD Dropout