A Nomogram to Predict Low PD Adequacy

Retrospective analysis of data from 141 incident PD patients compared between patients with and without adequate PD function, algorithms identified potential biomarkers, and significant predictors were integrated into a model to build a strongly predictive nomogram.

Read the abstract » | (added 2025-05-20)

Tags: Incident PD, PD Function, Biomarkers, Predictors, Nomogram

Expanded HD (HDx) vs. Online Hemodiafiltration (HDF)

A systematic review and meta-analysis of eight studies (n=614) compared HDx and HDF. While there was no statistical difference in all-cause mortality, creatinine, phosphate, or urea clearance, HDF did significantly reduce β2-microglobulin.

Read the abstract » | (added 2025-05-20)

Tags: HDx, HDF, Middle molecule Clearance

Cost of Home HD vs. Standard In-center HD in Dollars and Lives in France

Among 42,605 patients on HD in France (28,317 prevalent and 14,288 incident), 265 incident (53 at home) and 765 prevalent (153 at home) patients were propensity score matched to examine costs of care. For both incident and prevalent patients, the global costs of daily home HD were lower than for in-center—and in-center was associated with a 7-fold higher risk of death than daily home HD.

Read the abstract » | (added 2025-05-20)

Tags: Propensity Score, Costs Of Care, Mortality

Mechanism of AGE Damage to Peritoneal Membranes

Advanced glycation end-products (AGEs) are a well-known reason for peritoneal inflammation, though we didn’t know why. Researchers developed a way to study the Maillard reaction in collagen at near-physiological temperatures and found markedly increased permeability to small and medium-sized molecules as well as reduced proliferation of adherent mesothelial cells.

Read the abstract » | (added 2025-05-20)

Tags: Advanced Glycation End products, AGEs, Peritoneal Inflammation, Maillard Reaction

Glucose Exposure: Incremental vs. Full-dose PD

A 2-year retrospective study of 117 patients (46 incremental; 71 full-dose) with a 12 or more months of PD and 24-hour urine volume > 500 mL analyzed Q6-month cardiometabolic parameter trends: dry weight, BMI, HbA1c, cholesterol, serum glucose. HbA1c—lower in incremental PD users—was the only significant baseline difference between groups. The incremental group had significantly less estimated cumulative glucose exposure.

Read the abstract » | (added 2025-05-20)

Tags: Glucose Exposure, Incremental, Full dose PD, Cardiometabolic Parameter Trends

Guidelines Drive European Home Dialysis Practice

A consensus meeting held in Copenhagen, Denmark in 2023 investigated ways to improve home dialysis uptake, which was at a 10.5% prevalence and 13.3% incidence across Europe. Interestingly, national guidelines for advanced kidney care patient education drove uptake: home dialysis prevalence was significantly higher in countries with guidelines.

Read the abstract » | (added 2025-04-23)

Tags: National Guidelines, Advanced Kidney Care Patient Education, Home Dialysis Prevalence, Home Dialysis Uptake, Europe

Impact of Hurricane Helene on the PD Supply Chain

Hurricane damage to Baxter’s North Cove plant—which produces 60% of U.S. IV solutions—significantly disrupted patients’ ability to start or even continue PD. This analysis highlights healthcare vulnerabilities due to climate change.

Read the abstract » | (added 2025-04-23)

Tags: Hurricane, Emergency Planning, PD Supply

Seniors, PD, and Inappropriate Prescriptions

No study has previously assessed what percent of people over age 65 on PD are receiving the correct doses of prescribed drugs. Unfortunately, this study finds that a large minority may not be.

Read the abstract » | (added 2025-04-23)

Tags: Seniors, PD, Inappropriate Prescriptions, Correct Dose

Promising Ways to Increase Use of Home Dialysis

A scoping review of 43 studies categorized interventions to increase home dialysis uptake into three categories: education, service provision, and payment modifications. What worked best? Education aimed to enhance dialysis options knowledge and promote shared decision-making among patients, families, and clinicians and providing services like assisted PD. Payment intervention effectiveness depended on context.

Read the abstract » | (added 2025-04-23)

Tags: Home Dialysis, Home Modality, Patient Education, Provision, Home Dialysis Uptake, Shared Decision making

Uptake of Home Dialysis After Kidney Transplant Failure by Sex

An ANZDATA registry study analyzed dialysis after transplant failure of 3,521 patients from 2000 to 2020. While 38% of the patients were female, 12 months after transplant failure, 14% were using PD and 12% were using home HD. Males were 55% less likely to choose PD after transplant failure and 66% more likely to choose home HD. These disparities were greater in low SES regions.

Read the abstract » | (added 2025-03-13)

Tags: Gender, PD, Home HD, Transplant Failure