Journal Watch
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Metaanalysis of PD for Kidney Failure due to PKD
Polycystic kidneys may displace room for PD fluid, so can PD be a viable treatment option? A metaanalysis of 12 studies and more than 17,000 patients found…maybe. PD outcomes were about the same for those with PKD as with other primary kidney diseases, and some can do PD. More research is needed to determine who is suitable. Read the abstract.
Read the abstract » | (added 2018-10-12)
Tags: Dialysis Adequacy, PD associated Complications, Peritoneal Dialysis, Polycystic Kidney Disease
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PD and Dialysis Patient Employment
In a Swedish study, 4,734 working-age (20-60 years old) patients who survived at least one year on in-center HD or PD were compared. Patients using PD had a 4% increased probability of employment over in-center HD—as well as a 6% lower disability pension and higher work income. Read the abstract
Read the abstract » | (added 2018-10-12)
Tags: PD, HD, Employment, Disability Pension, Work Income
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Peritonitis Symptoms in Older vs. Younger People
A single center study compared the time to first episode of peritonitis treated successfully with antibiotics in PD patients >65 (n=79)compared to those who were younger (n=168). Of 377 peritonitis episodes, 126 were in the older group and 251 in the younger group. Older patients were less likely to have fever or cloudy dialysate as symptoms than younger patients, but rates of transfer to hemodialysis, relapse, hospitalization, and mortality were similar. Read the abstract.
Read the abstract » | (added 2018-10-12)
Tags: Peritonitis, Outcomes Of Peritonitis, Elderly PD, Patient PD
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Urgent Start PD + Diabetes
A retrospective study compared the first 30-day outcomes and survival trends of 80 urgent start dialysis patients, 50 of whom (62.5%) did PD. Compared to those who started standard in-center HD, the dialysis-related complications were significantly lower for those on PD, and PD survival was higher as well. Read the abstract.
Read the abstract » | (added 2018-10-12)
Tags: Diabetes, Survival Trends, Urgent Start Dialysis, PD, In center HD, Dialysis related Complications
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MXene Sorbents: A Step Toward a WAK
A sorbent tested for use in a wearable artificial kidney was able to adsorb urea with 99% efficiency in testing—twice the level removed with standard dialysate. The hemocompatible sorbent did not damage cells or reduce cell viability at the concentrations tested. A successful sorbent product will facilitate the design of a WAK. Read the abstract.
Read the abstract » | (added 2018-10-12)
Tags: Wearable Artificial Kidney, 2D Materials, Urea, MXene, Adsorption, Dialysate
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5-year study: Predialysis PD Education Saves Lives on PD
Among 398 patients who started PD from 2007-2016, 169 had received predialysis education. After 5 years, this group had a significantly lower rate of peritonitis, a longer median time to a first peritonitis episode, and less risk of death from peritonitis than patients who did not get CKD education. Read the abstract.
Read the abstract » | (added 2018-09-10)
Tags: PD, Predialysis, Peritonitis, Mortality, CKD Education
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Gender and Malnutrition in PD
Do hypoalbumineumia, overhydration, inflammation, and cardiovascular risk affect men and women on PD differently? A small study (N=26 men and 28 women) with comparable BMI found more fluid overload, inflammation, and heart risk in women with low serum albumin than in men. Read the abstract.
Read the abstract » | (added 2018-09-10)
Tags: Gender, Malnutrition, Cardiovascular Risk, Hypoalbuminemia, Inflammation, Overhydration, Peritoneal Dialysis
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PD Catheter Outcomes in Low vs. High-Volume Centers
Not surprisingly, patients whose PD catheters were placed at high-volume centers (in Japan) had fewer adverse events, needed feer blood transfusions, and had shorter hospital stays than those from low-volume centers. Read the abstract.
Read the abstract » | (added 2018-09-10)
Tags: PD, Catheter, Hospital volume
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Biocompatible PD Solutions Maintain Membranes Longer
Independently of inflammation, biocompatible PD solutions helped 71 patients keep a steady level of solute transport over 7.5 years, compared to 295 patients who used standard solutions. Read the abstract.
Read the abstract » | (added 2018-09-10)
Tags: Dialysis Solutions, Glucans, Glucose, IL6 Protein, Human, Inflammation, Interleukin 6, Peritoneal Fibrosis, Peritoneum, Peritonitis, Creatinine, Hospitalization, Icodextrin, Peritoneal Dialysis, Peritoneal Membrane
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Nocturnal HD is Underused
A new review suggests that the improved outcomes associated with more hours of HD in-center or at home mean that these options should be used more. Read the abstract.
Read the abstract » | (added 2018-09-10)
Tags: Extended Hours, Improved Outcomes, HD, Nocturnal Dialysis, Quality Of Life