Journal Watch
-
Daily HD Practices in France and Australia/New Zealand
Registry data from both regions compared all incident patients who dialyzed 5-6 sessions per week—both daytime and nocturnal—with one-to-one matching of French to Australia/New Zealand patients based on age, sex, and dialysis start year. While survival and transplant access were comparable, other intriguing differences appeared.
Read the abstract » | (added 2019-05-15)
Tags: Registry Data, Dialysis Interval, Survival, Transplant Acces
-
A Swan Song for Kt/V (It’s About Time!)
A new review of the flaws of Kt/V—including a lack of proof of concept—“leaves little room for any conclusion other than that Kt/V, as an indicator of dialysis adequacy, is obsolete.” [Editor’s Note: Now, if the authors would take on the concept of “adequate” vs. optimal therapy…]
Read the abstract » | (added 2019-05-15)
-
KDIGO Controversies: Dialysis Start and Modality Choice
A January 2018 Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference addressed significant variations between countries in dialysis start, patient preparation, and modality mix. Happily, attendees supported individualized care that incorporates patient goals and preferences (within quality and safety parameters), and the need to avoid a one-size-fits-all approach.
Read the abstract » | (added 2019-05-15)
Tags: Modality, Individualized Care, Patient Goals, Patient Preferences
-
NxStage HD and Removal of Beta-2 Microglobulin
Which works best to remove B2M, High-flux standard HD, post-dilution hemodiafiltration (HDF), NxStage short daily HD, or automated PD? In a small study (N=43), HDF and NxStage HD done 6 days per week removed the most B2M. Standard HD was next, with automated PD removing the least.
Read the abstract » | (added 2019-05-15)
Tags: B2m, High flux Standard HD, Post dilution Hemodiafiltration (HDF), NxStage Short Daily HD, Automated PD
-
Cognitive Impairment Predicts PD Peritonitis
A prospective cohort study assigned 458 PD patients to a cognitively impaired (CI) or non-CI group based on results of mental state testing. The groups were not otherwise significantly different. Over 31.4 (median) months, 94 patients had first-time peritonitis, and short-term memory losses were independently linked with a higher risk.
Read the abstract » | (added 2019-04-11)
-
Three Diuretics are Better than One on PD
A small study (n=51) randomly assigned adult CAPD patients to receive three diuretics or just one plus placebo for 6 months. Among the 43 patients who completed the trial, those who took three diuretics had significantly better hydration status and more change in urine output—with no adverse events reported.
Read the abstract » | (added 2019-04-11)
Tags: Peritoneal Dialysis, Furosemide, Hydration Status, Hydrochlorothiazide, Spironolactone
-
Operationalizing Telehealth for Home Dialysis
In January, 2019, Medicare rules for telehealth changed to permit the home as an originating site for home dialysis patients. ESCOs can take advantage of waivers to obtain payment for a monthly comprehensive telehealth visit with a home patient after the first 3 months of therapy—with no geographic restrictions. Technical, regulatory, and operational challenges are discussed in this article.
Read the abstract » | (added 2019-04-11)
Tags: Maintenance Dialysis Therapy, Telehealth Services, Legislation, Regulatory Requirements, Remote Monitoring
-
Perspectives on Payment for More Frequent Home HD
This article explains the role of the Medicare regional contractors in implementing—or thwarting—payment for more than three home HD payments per week, and offers options for changing Medicare’s payment system to ensure that this option is supported.
Read the abstract » | (added 2019-04-11)
Tags: Medicare Regional Contractors, Medicare Payment System, HD Payments
-
Clues to Home HD Retention
Why do people drop out of home HD? A new interview study of 15 current and 10 former patients sheds some light. The study identified five themes, each with a positive and a negative aspect: degree of independence, support, technical aspects, home environment, and attitudes and expectations.
Read the abstract » | (added 2019-03-12)
Tags: HHD, Modality, Discontinuation
-
HOW do AGE’s Cause Peritoneal Fibrosis?
For years, researchers have known that the advanced glycation endpoints (AGEs) that form when sugar-based PD fluid is made harm the membrane. But, we didn’t know why. Human cell modeling finds that AGEs cause outer layer peritoneal cells (epithelial) to become connective tissue cells (mesenchymal).
Read the abstract » | (added 2019-03-12)
Tags: AGEs, Mesothelial, Epithelial, STAT3