Journal Watch
GI Outcomes in PD Trials
A meta-analysis of 61 trials looking at patient-reported GI outcomes of PD mainly found nausea (43% of trials), diarrhea (43%), constipation (34%), abdominal pain (31%) and PD peritonitis (40%). But, only 19% of the available trials reported GI outcomes at all.
Read the abstract » | (added 2023-07-17)
Tags: GI Outcomes, PD, Nausea, Diarrhea, Constipation, Abdominal Pain, Peritonitis
Value of an Integrated Home Dialysis Model in the United Kingdom: A Cost-Effectiveness Analysis
This study aimed to determine the lifetime cost-effectiveness of increasing home hemodialysis as a treatment option for patients experiencing peritoneal dialysis technique failure compared with the current standard of care.
Read the abstract » | (added 2023-07-17)
Tags: Cost effective, Home Hemodialysis, Treatment Option, Peritoneal Dialysis Technique Failure
Does Incremental PD Preserve Residual Kidney Function?
Analysis of data from 154 patients in the randomized, controlled balANZ trial did not find a difference in the slope of ultrafiltration volume decline between full dose and incremental PD.
Read the abstract » | (added 2023-06-14)
Tags: Incremental PD, Residual Kidney Function, Ultrafiltration Volume
Intraperitoneal Sodium Thiosulphate for Calciphylaxis in PD
Calciphylaxis, or extraskeletal calciphylaxis is a rare, life-threatening condition. In a case series, researchers demonstrated that intraperitoneal delivery of sodium thiosulphate was a safe, convenient, long-term alternative to IV therapy.
Read the abstract » | (added 2023-06-14)
Portable, Wearable, and Implantable Artificial Kidneys
The need to continuously regenerate dialysate is a challenge for all portable, wearable, and implantable kidney replacement therapy options. Sorbent technology is one approach. New membrane materials can remove more uremic toxins than current ones. Combining these membranes with living kidney cells has potential as well.
Read the abstract » | (added 2023-06-14)
Tags: Dialysate, Portable, Wearable, Implantable Kidney, Kidney Replacement Therapy
UK Target: 20+% on Home Dialysis
Despite the many benefits of home therapies, PD and home HD remain underused. The UK now recommends a minimum 20% prevalence rate for home dialysis.
Read the abstract » | (added 2023-06-14)
Tags: PD, Home HD, Peritonitis
Daily HD and Cardiovascular Risk factors
In a 4-year study of 26 people using daily hemodialysis and 51 matched controls doing standard hemodiaysis, the daily treatments significantly improved blood pressure, calcium-phosphorus product, and hemoglobin levels. There was also a non-significant trend toward lower left ventricular mass index.
Read the abstract » | (added 2023-06-14)
Tags: Daily HD, Cardiovascular Risk Factors, Blood Pressure, Calcium phosphorus Product, Hemoglobin Levels
Hope Matters in PD
Among 134 patients receiving PD in Hong Kong, those who were working, had a higher income, and were using a cycler for PD had higher hope scores, and there were correlations with age and social support. Higher hope scores were linked with better mental well-being and less severe depression.
Read the abstract » | (added 2023-06-14)
Tags: PD, PD Cycler, Work, Hope Score, Social Support, Mental Well being, Depression
2023 ISPD Catheter Infection Recommendations
The updated recommendations have new definitions and classifications of exit site infection and tunnel infection, and new targets.
Read the abstract » | (added 2023-06-14)
Tags: Catheter, Infection, Exit Site Infection, Tunnel Infection, Antibiotic Treatment
Pathophysiology of Encapsulating Peritoneal Sclerosis (EPS)
EPS is a rare but often fatal complication of PD. Biopsy findings from Japan suggest that EPS is not sclerosis, but formation of a neo-membrane in response to a peritoneal injury.
Read the abstract » | (added 2023-06-14)
Tags: EPS, Sclerosis, Neo membrane