Journal Watch
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Dietary Protein Intake and Survival on PD
Among 668 stable PD patients followed for up to 13 years, quarterly 3-day dietary records were collected for 2 ½ years. Dietary protein intake greater than 0.8 g/Kg/day improved long-term survival.
Read the abstract » | (added 2023-12-15)
Tags: Dietary Protein, Survival, PD
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A Home Dialysis Primer for Internists
Since PD and home HD are increasing in use due to their clinical and practical advantages, clinicians need to understand these treatments. A new primer in the Annual Review of Medicine will help them do just that.
Read the abstract » | (added 2023-12-15)
Tags: Home Dialysis, HD, PD, Home Dialysis Primer
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How Sugar Harms the Peritoneum and Causes Fibrosis
HOW does sugar harm the peritoneum? An RNA sequencing study looked at peritoneal endothelial cell (EC) function in mice and human ESRD cells in the presence or absence of glucose. In mice, glucose increased EC proliferation, permeability, and inflammation. Blocking glucose caused a therapeutic benefit. Human cells reacted in a similar way.
Read the abstract » | (added 2023-12-15)
Tags: Sugar, Glucose, Peritoneum, RNA Sequencing, Endothelial Cell Function
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Hope, Quality of Life, and Psychoscial Distress in PD
Are people on PD hopeful? A study from China surveyed 134 people on PD, assessing their level of hope. Working patients with higher income using APD had higher hope scores, and hope correlated significantly with both age and social support. Higher hope scores were linked with better mental well-being and less severe depression.
Read the abstract » | (added 2023-11-15)
Tags: Hope, Quality Of Life, Psychoscial Distress In PD, Income, APD, Depression
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Home Dialysis and Psychological Health
An interview study of 36 people on PD (n=13) or home HD (n=7) and care partners identified four themes and subthemes, including isolation and disconnection, importance of support systems, burden of distress, and seeking mental health support.
Read the abstract » | (added 2023-11-15)
Tags: Isolation, Support Systems, Distress, Mental Health Support
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Surprising Impact of First Dialysis Modality on Survival in Patients with Diabetes
A retrospective cohort study of 739 patients from 2010 to 2018 (inclusive) used propensity score matching to compare mortality between standard HD and PD in China, matching 125 PD patients with HD patients. No significant differences were found—except in those with diabetes, who had significantly better survival with PD.
Read the abstract » | (added 2023-11-15)
Tags: Modality, Survival, Diabetes, Propensity Score Matching
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How to Set Up New Home Dialysis Programs
More than half of U.S. dialysis clinics are either not licensed to train patients in PD or home HD, or are licensed but have no patients in their home programs. A new review article outlines the core domains needed to set up and run a home dialysis program in the U.S.
Read the abstract » | (added 2023-11-15)
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Assisted PD in Europe
Not every PD patient can perform solo treatments—or has a care partner to help. Some European countries are offering assisted PD in the home, often temporarily, using a variety of PD prescriptions and care provided by private care agencies or nursing home staff. Tailoring the prescription to residual kidney function reduces PD burden and aids technique survival.
Read the abstract » | (added 2023-11-15)
Tags: Assisted PD
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Steady Glucose Concentration in PD and Sodium Removal
In a small pilot study (n=8), two fast-average and six fast transporters used a standard 4-hour CAPD dwell as a control, and three 5-hour steady-concentration treatments using the Carry Life® UF device following an overnight icodextrin fill as the intervention. UF rates were significantly higher with the steady glucose concentration treatments, as were sodium removal and glucose UF efficiency.
Read the abstract » | (added 2023-11-15)
Tags: PD, Glucose Concentration, Sodium Removal
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Rate of Residual Kidney Function Decline and Mortality in PD
When 497 PD patients were divided into two groups based on RRF decline value, those in the fast-decline group had significantly higher rates of all-cause and cardiovascular mortality. In fact, each 0.1mL/min/1.73m2 per month drop in RRF in the first year of PD predicted a 19% higher risk of all-cause mortality and a 20% higher risk of cardiovascular mortality.
Read the abstract » | (added 2023-11-15)
Tags: Rate Of Residual Kidney Function Decline, All cause Mortality, Cardiovascular Mortality