Journal Watch
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Better PD technique survival in people with diabetes who use icodextrin
In the first randomized control trial using icodextrin in lieu of glucose for PD solution, 41 people with diabetic nephropathy were assigned one or the other. After 2 years, 71.4% of the icodextrin group was still doing PD, while only 45% who used glucose-based solution still did PD.
Read the abstract » | (added 2011-04-25)
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Chemical ablation to correct recurrent secondary hyperparathyroidism post parathyroidectomy
Reoperation after a parathyroidectmy can be risky. In a study of 49 people, injecting ethanol (alcohol) into the gland, guided by ultrasound, helped to lower PTH levels without more surgery.
Read the abstract » | (added 2011-04-25)
Tags: Chronic kidney disease
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Benefits of switching from 3x/week in-center HD to 6x/week home HD
Among 11 people who switched treatments, blood pressure dropped, hemoglobin levels rose (with lower ESA doses), the calcium-phosphorus product dropped (with no change in binder doses), and BMI and serum albumin levels went up. We are so not surprised!
Read the abstract » | (added 2011-03-30)
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AAKP's study of patient satisfaction with kidney education and dialysis (hint: not so good)
977 patients completed a 46-item survey asking about satisfaction with current treatment for kidney failure and education on a scale of 1–10 (with 1 low). Standard in-center HD rated 4.5. PD rated 5.2, home HD was 5.5, and transplant was 6.1. About 31% of participants felt the treatment options were not equally and fairly presented, and 32% had not been educated about home HD.
Read the abstract » | (added 2011-03-30)
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PD (vs. in-center HD) and less bad breath
After 3 months on PD, 42 people in a new study had more saliva—and less bad breath.
Read the abstract » | (added 2011-03-30)
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Better fluid removal with icodextrin PD fluid - Meta-analysis
A new study of 9 randomized controlled trials has found that people using icodextrin removed much more water than those using glucose based fluid—with no change in residual kidney function or increase in peritonitis or death. Rash was more common in those using icodextrin.
Read the abstract » | (added 2011-03-30)
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Simpler pill regimen needed by those using nocturnal home HD
Among 35 people who switched from standard in-center HD to nocturnal home HD, the number of pills per day did not drop—but the regimen was much simplified—and health-related quality of life was significantly improved.
Read the abstract » | (added 2011-03-30)
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Wearable artificial kidney a step closer?
A company called National Quality Care presented its newly patented wearable artificial kidney (WAK) at the recent American Society of Nephrology meeting in Philadelphia. Invented by Dr. Victor Gura, the WAK is vastly smaller than current machines, and will permit 24/7 dialysis. Read more to learn how it will work.
Read the abstract » | (added 2011-02-24)
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Study finds survival advantage for home hemo over in-center
A new retrospective Swiss study (Nephrology Dialysis Transplantation Jan 2005, 20:604-610) matched 58 home hemo (HHD) patients with 58 in-center patients on sex, age, length of time on dialysis, and cause of kidney failure. The researchers found better survival among the HHD patients at 5 (93% vs. 64%), 10 (72% vs. 48%), and 20 years (34% vs. 23%).
Read the abstract » | (added 2011-02-24)
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Human trial reports on wearable artificial kidney (WAK) in UK
The competition for better home HD gets even hotter! The December 2007 edition of Lancet includes an article about use of the WAK in 5 men and 3 women, who tried the device for 4–8 hours. There were no adverse heart, electrolyte, or acid-base events—though some access problems did occur, and dialysis itself is not yet optimal. It's still cool, though.
Read the abstract » | (added 2011-02-24)
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