Journal Watch
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Risk factors linked to renal cell cancer (RCC) after long-term dialysis
RCC occurs at higher rates in those who have been on dialysis for many years. If you know the risk factors, you can ask for screening. Those at highest risk in a large study were men; older people; ESRD caused by an obstruction, FSGS, or tuberous sclerosis; and those whose kidneys grew new cysts.
Read the abstract » | (added 2011-06-21)
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Statin use may boost PD survival
A new study from Korea has found that taking a statin drug to lower cholesterol helped people on PD live longer—whether or not they had diabetes. The researchers suggest that larger, randomized studies are now needed.
Read the abstract » | (added 2011-06-21)
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NAC protects PD membrane from sugar damage in rats
Over time, caramelized sugars in PD fluid can scar the peritoneal membrane to the point where PD may no longer work. In a rat study, an antioxidant (N-acetylcysteine, or NAC) reduced this damage. NAC may one day prove to be a treatment for humans.
Read the abstract » | (added 2011-06-21)
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Bone loss in women on dialysis—the role of estrogen
A study of 112 postmenopausal women on HD in Japan found that estrogen was closely linked to bone density. The authors conclude that taking estrogen may help prevent bone loss throughout life in women on HD.
Read the abstract » | (added 2011-05-23)
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A prospective study of 4 vs. 8 hours of HD in-center 3 times a week
Which is better, standard HD or more HD? A new study matched 247 people who agreed to try nocturnal in-center HD with people on standard HD. A year later, survival rates were 3.5 times higher (and hospital stays were lower) with more HD. Heart health and cognitive function were far better with more HD, too, while quality of life dropped in the standard HD group. (Now, why are we NOT surprised?)
Read the abstract » | (added 2011-05-23)
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Cycler PD has better outcomes than manual PD for those under age 65
Among 282 people on PD, younger people were much more likely to keep doing PD—and much more likely to survive—if they used a cycler.
Read the abstract » | (added 2011-05-23)
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New model using routine lab tests can predict progression to kidney failure
Researchers looked at data from a total of 8,391 people with stages 3–5 CKD to see if lab test results could predict who would progress to end-stage. A model that included age, sex, GFR, and protein in the urine worked best.
Read the abstract » | (added 2011-05-23)
Tags: Chronic kidney disease
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CKD education rates in Australia (they're FAR better than in the US!)
It's hard to choose a treatment option for kidney failure that fits your life when you don't know what the options are, or how they might affect you. A study of 721 people new to dialysis in Australia found that 603 (84%) had options education before they started treatment.
Read the abstract » | (added 2011-05-23)
Tags: Chronic kidney disease
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Eating more protein improves survival on PD
How much protein is enough on PD? In a study of 305 people on PD, getting 0.94 grams of protein per kilo of body weight per day was linked to much better survival. So if you weigh 68 kilos (150 lbs.'), you'd need at least 64 grams of protein a day—about 2 and a quarter ounces. You can do that!
Read the abstract » | (added 2011-05-23)
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Australian nephrologists say PD first, then nocturnal HD
A lengthy survey of Australian nephrologists found strong agreement that long HD is a good option—most easily done at home, and that PD is a great first choice for dialysis. In fact, 34% of respondents said their clinic had a "PD First" policy.
Read the abstract » | (added 2011-05-23)
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