Journal Watch - HDF
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Hemodiafiltration versus High-flux Hemodialysis and Risk of Mortality: A Multinational Target Trial Emulation
A Fresenius study of almost 20,000 patients in eight European countries from 2014-2019 found that hemodiafiltration (HDF) reduced all-cause mortality risk by 28% over conventional high flux HD. Even better, all-cause mortality was reduced 33% with high volume (23 liters per session) HDF compared with conventional high flux HD.
Read the abstract » | (added 2026-09-18)
Tags: Hemodiafiltration, HDF, All cause Mortality
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Expanded HD (HDx) vs. Online Hemodiafiltration (HDF)
A systematic review and meta-analysis of eight studies (n=614) compared HDx and HDF. While there was no statistical difference in all-cause mortality, creatinine, phosphate, or urea clearance, HDF did significantly reduce β2-microglobulin.
Read the abstract » | (added 2025-05-20)
Tags: HDx, HDF, Middle molecule Clearance