Journal Watch
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Fatigue at PD Start Linked with Higher Mortality
A PLOS One study compared 4,285 incident PD patients who completed a KDQOL-SF vitality scale from Brazil (1,388) and the U.S. (2,897) from 2004 to 2011. Lower vitality scores after 90 days of PD were linked with a higher risk of mortality in both countries
Read the abstract » | (added 2022-07-13)
Tags: Fatigue, Incident Peritoneal Dialysis, Vitality, Mortality
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Structured CKD Education More Than Tripled Uptake of Home Therapies
In a matched retrospective cohort study, 2,398 CKD patients who attended a single 90-minute education program were pair-matched with others who did not. Compared to controls, those who attended the session were significantly more likely to be doing home dialysis (38.5% vs. 12.6%) and to be using a permanent access (57.9% vs. 33.8%). Hospitalization rates were 38% lower as well, and education-attendees had lower first-year mortality.
Read the abstract » | (added 2022-07-13)
Tags: CKD, Education Program, Home Dialysis, Permanent Access, Hospitalization Rates, First year Mortality
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Some WILL Choose More Intensive HD—If They Learn the Benefits
In the UK, a new study of 183 in-center HD patients finds that 60+% would consider doing 4 treatments per week or 4.5 hours per treatment. Information about longer survival, better quality of life, and fewer fluid limits and access complications were all significantly linked with choosing longer and/or more frequent treatments.
Read the abstract » | (added 2022-06-10)
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Home HD Patients Grasp Fluid Management Better than In-Center Ones
Compared to 839 people on in-center HD in the UK from six clinics, 99 receiving home HD had significantly more knowledge about fluid management and signs and symptoms of fluid overload. They also felt more in control and reported better adherence—though knowledge gaps remained.
Read the abstract » | (added 2022-06-10)
Tags: In center HD, Home HD, Fluid Management, Fluid Overload, Ckd Education
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Surprise Supplement Reduced Risk of Peritonitis on PD
Does correction of hypokalemia with potassium supplementation impact peritonitis rates? Yes, finds a new randomized controlled trial of 167 PD patients with hypokalemia from six clinics. Compared to conventional potassium management, use of a protocol aimed at maintaining potassium levels at 4-5mEq/L significantly extended time to first peritonitis.
Read the abstract » | (added 2022-06-10)
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In Which Countries Do People Stay on PD Longer?
The Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS) analyzed time on PD among 218 randomly chosen clinics and 7,121 patients in seven countries including the U.S. Median time on PD ranged from 1.7 years in the UK to 3.2 years in Japan and Thailand. PD mortality risk was higher in Thailand and the U.S., and infection was the leading cause of transfers to HD.
Read the abstract » | (added 2022-06-10)
Tags: Peritoneal Dialysis Outcomes And Practice Patterns Study, PDOPPS, PD, Mortality, Hemodialysis Transfer, Kidney Transplantation
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Risk of Left Ventricular Hypertrophy Tied to Fluid Overload on PD
A single hospital had 226 enrolled PD patients between late 2018 and January 2021. Using bioimpedance analysis and cardiac color Doppler ultrasound, patients were divided into an LVF and a non-LVF group, and into a normal volume and overhydration group. Of participants, 125 (55.3%) had LVH. Overhydration and low hemoglobin levels were independent risk factors for LVH.
Read the abstract » | (added 2022-06-10)
Tags: PD, LVH, Overhydration, Volume Loads
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Meta-analysis of Omental Procedures with PD Catheter Placement
Should removal (omentectomy) or fixation in place (omentopexy) of the curtain of omentum tissue be routine when a PD catheter is placed? In 15 studies (with low-to-moderate evidence), omental procedures reduced the risk of a need to remove the PD catheter. There were no differences in catheter malposition, migration, or peritonitis.
Read the abstract » | (added 2022-05-12)
Tags: Omentectomy, Omentopexy, Omentum Tissue, PD Catheter, Catheter Malposition, Migration, Peritonitis
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Urgent Start PD Takes on Urgent Start HD—Which One Wins?
A new meta-analysis examines survival vs. urgent start HD (which is experienced by an estimated 50%-60% of U.S. dialyzors). Pooled data from seven studies identified “a statistically significant reduced risk of all-cause mortality in patients undergoing urgent-start PD as compared to urgent-start HD.” While infectious complications did not differ, there was a significantly reduced risk of mechanical complications with PD.
Read the abstract » | (added 2022-05-12)
Tags: Urgent Start PD, Urgent Start HD, Survival, All cause Mortality, Mechanical Complications
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Early Data from the Physidia Home HD Machine
The Physicia S3 is a new home HD machine in France that uses bagged fluid. A new proof-of-concept study enrolled 13 training centers and analyzed data from 80 patients and 249 treatment sessions. Dialysis dose, anemia, nutrition, and electrolytes were all adequately controlled.
Read the abstract » | (added 2022-05-12)
Tags: Physicia S3, Bagged Fluid, End stage Kidney Disease, Portable Artificial Kidney