New Nomogram Predicts Roxadustat Treatment Failure in Anemic PD Patients

A retrospective analysis of 204 anemic PD patients from 2019 to 2023 was used to construct a predictive nomogram of Roxadustat success. Duration of PD, serum transferrin, cardiovascular comorbidities and stains were significant predictors. The nomogram was more predictive at 12 months than at 6 months.

Read the abstract » | (added 2024-04-12)

Tags: Roxadustat, HIF inhibitor, Treatment Failure, Anemia, PD

Comprehensive Health Education and PD

Among 98 PD patients randomly assigned to routine care or a full-course health education program, the full-course group had significantly higher health behavior and treatment adherence scores. They were more likely to take their medications correctly and had better quality of life and fewer hospital readmission rates than controls.

Read the abstract » | (added 2024-04-12)

Tags: Peritoneal Dialysis, PD, Comprehensive Health Education, Education Program, Quality Of Life

Mineral Bone Disease (MBD) and Survival on PD

A P-DOPPS study analyzed MBD data from more than 12,000 patients from eight countries. The results revealed a U-shaped curve for the relationship between PTH and mortality, with the lowest risk at PTH levels of 300-599 pg/mL. Serum calcium levels higher than 9.6 mg/dL were associated with a 20% increase in mortality as well. Major country variations in MBD treatment were identified.

Read the abstract » | (added 2024-04-12)

Tags: Mineral Bone Disease, MBD, PTH, Mortality, Serum Calcium Levels, PD

The effect of urgent-start peritoneal dialysis and urgent-start hemodialysis on clinical outcomes in patients with chronic kidney disease: an updated systematic review and meta-analysis

Recently, urgent-start peritoneal dialysis (PD) has been suggested in place of urgent-start hemodialysis (HD) in cases of chronic kidney disease (CKD). However, the comparative effectiveness of these methods is still unclear. This study compared the outcomes of urgent-start PD and urgent-start HD in CKD patients.

Read the abstract » | (added 2024-03-15)

Tags: Dialysis related Complications, Hemodialysis, Kidney Disease, Mechanical Complications, Mortality, Peritoneal Dialysis, Renal Replacement Therapy

Impact of Prior Abdominal Procedures on Peritoneal Dialysis Catheter Outcomes: Findings From the North American Peritoneal Dialysis Catheter Registry

A history of prior abdominal procedures may influence the likelihood of referral for peritoneal dialysis (PD) catheter insertion. To guide clinical decision making in this population, this study examined the association between prior abdominal procedures and outcomes in patients undergoing PD catheter insertion.

Read the abstract » | (added 2024-03-15)

Tags: Dialysis, PD, PD Catheter Outcomes, End Stage Kidney Disease, Peritoneal Dialysis, Prior Abdominal Surgery

Impact of the START Project on PD in Canada

In Alberta, Canada, the Starting dialysis on Time, at home, on the Right Therapy (START) project enrolled 1,962 consecutive adult ESKD patients who started dialysis between April 1, 2015 and March 31, 2018 with the aim of increasing the proportion of patients who do PD within 6 months of dialysis start. At baseline, 27% of incident patients tarted PD. Immediately after implementation, there was a 5.4% increase in the use of PD. No changes were found in rates of hospitalization, death, or probability of switching to HD.

Read the abstract » | (added 2024-03-15)

Tags: Haemodialysis, Peritoneal Dialysis, Quality Improvement

Meta-analysis of Urgent Start vs. Conventional Start PD

Analysis of data from 27 studies found comparable post-procedure infections, peritonitis, and exit site infections, technique survival, and transfer to HD for urgent and conventional start PD. Urgent start PD had a signficantly higher risk of mechanical complications such as leaks, and significantly higher mortality rates.

Read the abstract » | (added 2024-03-15)

Tags: Chronic Kidney Disease, Meta analysis, Peritoneal Dialysis

Non-mesh Inguinal Hernia Repair with Early CAPD Resumption

Thirty CAPD patients with 43 inguinal hernias underwent non-mesh repair between May, 2019 and September, 2023. Patients resumed PD at a median of 2 days post-surgery. There were no surgical or uremic complications or hernia recurrences. Interim HD was not necessary.

Read the abstract » | (added 2024-03-15)

Tags: Hernia Repair, Inguinal Hernia, Non mesh Herniorrhaphy, Peritoneal Dialysis

Short Daily HD, Muscle Strength, and Bone Health

A cross-sectional study compared a variety of parameters between 86 conventional HD patients and 92 short daily HD patients. The short daily HD patients had significantly higher serum albumin levels, Kt/V, and bone mineral density, required significantly fewer ESAs, and had lower phosphorus, inflammation, and PTH levels than conventional HD patients. Short daily HD patients also had significantly higher scores on the 6-minute walking test, stronger hand grips, lower fasting blood sugars, and higher hemoglobin levels.

Read the abstract » | (added 2024-02-07)

Tags: Bone Mineral Density, Conventional Haemodialysis, End stage Kidney Disease, Inflammation, Muscle Function, Short daily Haemodialysis

Cardiovascular Outcomes Compared in PD vs. Home HD

Data from almost 69,000 patients in the USRDS who started PD or home HD to assess for rates of hospitalizations due to incident cardiovascular events (acute coronary syndrome, heart failure, stroke). While the unadjusted rate of cardiovascular events was higher in home HD than PD patients, the adjusted rates were lower for stroke and acute coronary syndrome. There was no difference in heart failure risk, but home HD was linked with a 22% lower adjusted risk of cardiovascular death.

Read the abstract » | (added 2024-02-07)

Tags: USRDS, PD, Home HD, Hospitalization Rate, Incident Cardiovascular Events